Portanto, meios clínicos para o diagnóstico podem ser úteis. O diagnóstico do transtorno comportamental do sono REM (TCSREM) implica na realização da polissonografia (PSG), mas sua disponibilidade pode não ser suficiente. Parkinson’s Disease REM Sleep Behavior Disorder Brazil Polysomnography Surveys and Questionnaires The instrument is also valid and may help in a better selection of cases for a more detailed clinical evaluation or even PSG analysis. RBDSQ-BR is a reliable instrument, which may be useful for RBD diagnosis of Brazilian patients with PD. Items 2 and 6.2 had 84.2% specificity and 3.2 LR+. A cut-off score of 4 enabled the correct diagnosis of 76.8% subjects and provided the best balance between sensitivity (84%) and specificity (57.9%), with a 2.0 likelihood ratio of a positive result (LR+) and a 0.3 likelihood ratio of a negative result (LR-). The receiver operating characteristic (ROC) curve analysis had an area under the curve (AUC) of 0.728. The retest performed in a second sample (n=13, consecutive) showed high agreement for total score (intraclass correlation coefficient, ICC=0.863) and acceptable agreement for items 2, 3, 6.2, 6.3, 7, and 8 (K>0.60). RBDSQ-BR showed adequate internal consistency (Cronbach’s α=0.809) and, except for item 8, adequate item-test correlation. Using detailed clinical interviews and PSG analysis (diagnostic gold standard), a convenience sample of 69 subjects was divided into the following subgroups: patients with PD and RBD (PD+RBD n=50) and patients with PD alone (PD-RBD n=19). To validate the Brazilian Portuguese version of RBD screening questionnaire (RBDSQ) for patients with Parkinson’s disease (PD). In these situations, a clinical diagnostic measure might be useful. However, PSG may not be sufficiently available. About the authorsĪ diagnosis of rapid eye movement sleep behavior disorder (RBD) currently requires confirmation with polysomnography (PSG). Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto, São Paulo SP, Brazil.
Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto, São Paulo SP, Brazil.Universidade Federal de São Carlos, Centro de Ciências Biológicas e da Saúde, São Carlos SP, Brazil. Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto, São Paulo SP, Brazil.Universidade Federal do Ceará, Faculdade de Medicina, Fortaleza CE, Brazil.